Recombinant D. melanogaster Hsc70-interacting protein 1(HIP)

Species	Drosophila melanogaster
Target Names	HIP
Alternative Names	HIP; CG32789
Expression Region	1-377
Subcellular Location	Cytoplasm.
Protein Families	FAM10 family
Function	One HIP oligomer binds the ATPase domains of at least two Hsc70 molecules dependent on activation of the Hsc70 ATPase by Hsp40. Stabilizes the ADP state of Hsc70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of Hsc70 with various target proteins.
Database Info	KEGG: Dmel_CG2947; STRING: 7227.FBpp0070575; UniGene: Dm.33464

Product Type	Recombinant Protein
Source	Yeast; E. coli; Baculovirus; Mammalian cell
Target Protein Sequence	MAFTMQTGDL KKLKYFIDFA LENPTFLNMP QLQFVKDFVE KFGGTVPPGQ FNGGSAGGKC PFGGVAGAKA NEPANAPEDS EDEKSLSDPE SDVELDMEGV IEADSDPAQP MGNYSKKATE EEVEQASELR AQAASAYGQQ KFDEAIALYT KAIELSPGNA LFHAKRGQAF LKLKKPNACI RDCDVALELN SDLAAGYKFR GRARRLLGDF ELAAHDLRQA CKLDFDEETD EWLKEVTPNA KKIEQHRLKQ ERRQAERKIK ERQRDQRRAR KEQEKHNASS GGSSGEFSGG NPGNGNMSDI LGAMSDPEVS AAIQDILSNP GNITKYASNP KIYNLIKKIV PGGDVGAAFG QAGEKAGKPS EPKPKKDSAD FVDDGLD
Protein Length	Full Length Protein
Purity	>85% (SDS-PAGE)
Tag Info	The following tags are available. N-terminal His-tagged Tag-Free
Form	Lyophilized powder
Buffer before Lyophilization	Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Lead Time	Delivery time may differ from different purchasing ways or locations, please kindly consult us for specific delivery times.

Storage Condition	Store at -20 °C/-80 °C upon receipt, aliquoting is necessary for multiple use.
Shelf Life	The shelf life is related to many factors, including storage state, buffer ingredients, storage temperature, and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C.
Handling	Repeated freezing and thawing are not recommended.
Limitations	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Store working aliquots at 4 °C for up to one week.

For research use only. Not intended for any clinical use.