Drosophila Neurons Electrophysiological Analysis Service

Nerve cells are transmitting information through rapidly changing electrical signals. The study of the Drosophila nervous system must be done with the help of electrophysiological techniques. The function of a particular neuron is verified by (large scale) measuring the action potential of neurons and targeting the neural circuits involved in the target physiological activity.

CD BioSciences enables electrophysiological recordings of Drosophila brain tissue or individual neural circuits with sub-millisecond precision through an advanced electrophysiological technology platform. Our services enable recording of neural activity in the microenvironment, including receptors and targets, intra-membrane and intracellular signaling signals. CD BioSciences provides a total solution for in vivo Drosophila extracellular recording, intracellular recording and membrane clamp electrophysiological recording to support our clients' neuroscience research.

Fig.1 Electrophysiological Method for Recording Intracellular Voltage Responses of Drosophila (Juusola et al, 2016)

Our Service

CD BioSciences provides total solutions for electrophysiological analysis of Drosophila in vivo and neural cells in vitro. We are dedicated to cutting-edge research in Drosophila brain and neuroscience, addressing our customers' technical strongholds in patch-clamp technology and electrophysiological analysis. Combined with our Drosophila dissection and internal signal processing platform, we accelerate your research projects and save you time.

• Patch-Clamp Electrophysiological Techniques
  The patch-clamp technique is the most widely used intracellular recording technique for Drosophila in vivo potential measurements, such as visual systems, motor nerve systems and synaptic responses. A glass microelectrode tip is placed in close contact with the cell membrane, with only μm of contact area for conducting ions, and current is monitored based on a constant voltage across the membrane, allowing accurate measurement of multiple potentials including membrane potential, excitatory postsynaptic potential (EPSP), inhibitory postsynaptic potential (IPSP), and action potential. CD BioSciences offers a variety of patch clamp technology services, including cell-attached mode, inside-out mode, outside-out mode, whole-cell mode, and perforated patch mode.

• Extracellular Potential Recording
  CD BioSciences provides a holistic service of extracellular recording of electrophysiology by placing electrodes on the surface of neural tissue to record the electrical activity of nearby neural tissue. Extracellular electrophysiological recordings are able to detect local potential fields and characterize regional neuronal population collaboration information. Although extracellular recordings are simple to perform, the amplitude and waveform of recorded potentials vary greatly with electrode location. Therefore, we recommend it for recording inter-neuronal activity.

General Workflow

Why CD BioSciences?

• Rich experience in Drosophila electrophysiological analysis
• Professional electrophysiological platform
• Reliable experimental data with good repeatability
• Fast turnaround, cost-effective and transparent pricing

CD BioSciences is an expert in fruit fly field. We provide professional solutions for Drosophila in situ electrophysiological analysis. Our team of professionals provides 24 × 7 customer service to every client for saving time and effort. There are no limitations of our service. If you need any further information or have any question, please feel free to contact us.

Reference

• Juusola M, et al. (2016). Electrophysiological method for recording intracellular voltage responses of Drosophila photoreceptors and interneurons to light stimuli in vivo. JoVE. 112.

For research use only. Not intended for any clinical use.

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