Drosophila Neural Circuits Analysis Service
Drosophila is the model animal of choice for studying the gene - neural circuit - behavior relationship. The Drosophila brain has approximately 100,000 neurons that form a vast number of neural circuits that perceive external stimuli, process information, and respond. Furthermore, the Drosophila brain also has advanced functions such as learning and memory. Neural circuits can be composed of multiple neurons through chemical and electrical synapses. Therefore, measuring the activity of neurons and characterizing their connections through a variety of physicochemical and imaging techniques is important for identifying the function of neurons, mapping Drosophila neural networks, and facilitating the development of drugs for neurological disease targets.
CD BioSciences has established an advanced Drosophila neuron and circuit detection technology platform, including in vivo and in vitro examination of neurons connection. Our Drosophila electrophysiology, calcium imaging and neurotransmitter analysis technologies can detect every neuron at single-cell resolution, or even all associated neurons in a specific region, accelerating our customers' progress in studying Drosophila neural circuits.
Fig.1 Sleep-regulating circuits in D. melanogaster brain (Dissel et al, 2020)
CD BioSciences is dedicated to the study of Drosophila neuronal function, including electrical and chemical synapses. We provide comprehensive technology and advanced equipment for Drosophila neural circuits analysis. CD BioSciences develops the best strategic plan for our clients to meet the specific requirements of the project.
Calcium imaging is a technique that uses microscopic imaging systems to monitor changes in neuronal calcium concentrations and thereby detect neuronal activity. CD BioSciences provides customers with highly sensitive, signal-stable chemical and genetically encoded calcium indicators, as well as high quality imaging.
Electrophysiological techniques are used to detect neural circuits or brain regions involved in the regulation of neural activity and behavior by detecting potentials and currents in single neuron or cell subgroups. CD BioSciences provides in vivo and in vitro electrophysiological analysis, including dissection, system commissioning, data acquisition, signal amplification and conversion, data analysis, and other overall services to meet the needs of various development states and parts in Drosophila.
Signal transduction at chemical synapses is dependent on the release and reception of neurotransmitters. Using electrophysiological and calcium imaging techniques, their bioelectrical signals are not fully captured. Therefore, CD BioSciences provides Drosophila neurotransmitter analysis based on chromatography, mass spectrometry and electrochemistry platforms for dynamic and highly sensitive detection of spatiotemporal and low-level expressed neurotransmitters to accelerate customer research.
Why CD BioSciences?
CD BioSciences is an expert in Drosophila Neuroscience. We provide expertise in Drosophila neuron and neural circuit analysis. Advanced research team and strict quality control ensure fast project turnaround and excellent quality. Our team of professionals provides 24 × 7 customer service to every client for saving time and effort. There are no limitations of our service. If you need any further information or have any question, please feel free to contact us.
- Prokop A. (2016). Fruit flies in biological research. Biological Sciences Review. 28(2), 2-5.
- Dissel S. (2020). Drosophila as a model to study the relationship between sleep, plasticity, and memory. Frontiers in physiology. 11, 533.
For research use only. Not intended for any clinical use.