Drosophila Gene Editing Service
CD BioSciences specialize in cutting-edge techniques for precise genetic modifications in Drosophila, the fruit fly model organism. Our services include Drosophila CRISPR/Cas9 Genome Editing, Drosophila TALEN Genome Editing, and Drosophila Seamless Gene Editing. Our expert team specializes in leveraging advanced techniques to manipulate the Drosophila genome, enabling breakthrough discoveries in biological sciences.
Introduction to Gene Editing in Drosophila
The gene editing of Drosophila is a process that uses biotechnological methods to edit and regulate genes within an organism, leading to the organism's modification. In Drosophila, this process encompasses gene knockout, gene mutation, and the introduction of exogenous genes. Scientists can alter or delete specific genes using gene editing technologies, notably CRISPR-Cas9, enabling them to study the functions of these genes, and even create Drosophila with unique characteristics.
Fig 1. In vivo genome editing with the Cas12a system offers several technical complements relative to standard Cas9-based editing in Drosophila. (Ewen-Campen.; et al. 2020)
CRISPR/Cas9, a revolutionary gene-editing tool, is utilized to introduce targeted genetic changes in Drosophila. It consists of a guide RNA that guides the Cas9 enzyme to the desired DNA sequence, where it makes precise cuts. These cuts can be repaired by the cell's natural DNA repair mechanisms, leading to gene mutations or allowing the insertion of new genetic material.
Gene editing in Drosophila has enabled researchers to unravel the complex genetic mechanisms underlying various biological processes. It has facilitated the discovery of new genes, the study of gene interactions, and the development of novel therapeutic approaches.
Drosophila serves as a valuable model system, offering insights into human genetics and advancing our understanding of fundamental biological principles. CD BioSciences provides Drosophila gene editing service, including but not limited to:
CD BioSciences provides Drosophila CRISPR/Cas9 gene editing service, which utilizes the CRISPR/Cas9 system to achieve a variety of gene editing operations, such as gene knockout, point mutation, and conditional gene knockout, by targeting DNA cleavage through the RNA-guided nuclease Cas9.
CD BioSciences provides Drosophila TALEN gene editing service, which utilizes TALEN (Transcription Activator-Like Effector Nuclease) to be able to recognize specific DNA sequences and cleave them, thus enabling operations such as gene knockout, point mutation, and conditional gene knockout.
CD BioSciences offers Drosophila seamless gene editing service, which enables the precise repair of the Drosophila genome to produce a whole-chromosome copy with a specific gene mutation. This is accomplished by introducing the desired mutation at the Cas9 cleavage site, enabling seamless editing.
Want to Learn More?
CD BioSciences specialize in providing exceptional services in the field of Drosophila research. Whether you require the generation of transgenic Drosophila lines with specific genetic modifications or need assistance in designing and optimizing your experiments, our customized gene editing service offer a reliable and efficient solution. Contact us to discuss your research needs and learn how we can contribute to your scientific endeavors.
- Ewen-Campen.; et al. Expanding the horizons of genome editing in the fruit fly with Cas12a. Proceedings of the National Academy of Sciences. 2020, 24019-24021.
For research use only. Not intended for any clinical use.