Anti-D. melanogaster SIAH2 Monoclonal Antibody (24E6H3)

SIAH2

The Drosophila SINA (seven in absentia) protein is an E3 ubiquitin ligase component of the RAS signal transduction pathway. The RAS signal pathway controls cell proliferation, differentiation, and survival, and regulation of this pathway is critical for normal development. In Drosophila SINA serves as a downstream gatekeeper required for proper RAS signal transduction. Similarly to SINA in Drosophila, the human protein SIAH has also been shown to be required for oncogenic RAS signaling in cancer.

Mouse

Monoclonal

IgG1

Non-conjugated

Tissue culture supernatant

Synthetic peptide made to an N-terminal portion of the Drosophila melanogaster SINA protein (within residues 1-100).

Liquid

Tissue culture supernatant

Made-to-order

WB, Flow, Flow-IC, ICC/IF, IHC, IHC-Fr, IHC-P

Drosophila melanogaster

Store at -20 °C or -80 °C.

Avoid freeze-thaw cycles.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.