Anti-D. melanogaster PolA2 Polyclonal Antibody
- Catalog Number: CDDMAB-3120009
- Size: 100 μL; 50 μL; More Options
Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit PolA1, an accessory subunit PolA2 and two primase subunits, the catalytic subunit Prim1 and the regulatory subunit Prim2) is recruited to DNA at the replicative forks. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on the lagging and leading strand, respectively.
Protein A or G purified
Recombinant Drosophila melanogaster PolA2 protein.
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
It differs from different batches. Please contact us to confirm it.
Storage & Handling
Store at -20 °C or -80 °C.
Avoid freeze-thaw cycles.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
For research use only. Not intended for any clinical use.