Anti-D. melanogaster HSP70/HSPA1A Monoclonal Antibody

HSPA1A

Heat shock proteins are produced by prokaryotic and eukaryotic cells, and are among the most conserved molecules in phylogeny. Eukaryotic cells contain an Hsp70 (BRM-22) multigene that differ in their intracellular location and regulation. Members of the Hsp70 (BRM-22) family play a major role in the folding, unfolding and translocation of polypeptides as well as in the assembly and disassembly of oligomeric protein complexes, as well as in the immune response. Hsp70 (BRM-22) was found to increase dramatically in the brains of Alzheimer's disease patients, and was localized exclusively in neuritic plaques and neurofibrillary tangles. Hsp70 (BRM-22) concentrates in nuclei during heat shock and returns to the cytoplasm when the shock is removed.

Mouse

Monoclonal

IgG1

Non-conjugated

Unpurified

Full length native protein (purified) (Bovine brain).

Liquid

Ascites

It differs from different batches. Please contact us to confirm it.

Made-to-order

WB, ELISA, EM, Flow, IHC, IHC-Fr

Drosophila melanogaster

Store at -20 °C or -80 °C.

Avoid freeze-thaw cycles.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.