Anti-D. melanogaster Cytochrome c Monoclonal Antibody - BSA Free

CYCS

In addition to its well-known role in electron transport, cytochrome c (CYT) has been identified as a mediator of apoptosis or programmed cell death. Cytochrome c translocates from mitochondria into the cytoplasm in the early phases of apoptosis and plays a role in initiation of the apoptotic proteolytic cascade by activating caspase-3. Cytochrome c has been shown to bind Apaf-1. Apaf-1 has also been shown to activate capase-3.

Mouse

Monoclonal

IgG2b Kappa

Non-conjugated

Protein G purified

Synthetic peptides corresponding to amino acids 1-80, 81-104 and 66-104 of pigeon CYT were used as the immunogen. The antibody recognizes an epitope within amino acids 93-104 of pigeon cytochrome C based on competitive ELISA results.

Liquid

PBS, pH 7.4

1.0 mg/mL

Made-to-order

WB, Simple Western, Flow, Flow-CS, Flow-IC, IB, ICC/IF, IHC, IHC-P

Drosophila melanogaster

Store at -20 °C or -80 °C.

Avoid freeze-thaw cycles.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.