Anti-D. melanogaster chinmo Polyclonal Antibody

chinmo

33343

Required for morphological differentiation of postmitotic neurons during postembryonic brain development. Ensures production of appropriate neuron subtypes within a lineage by preventing precocious generation of late neuronal types of that lineage. Acts as a downstream mediator of the transcriptional activator Stat92e and is required for the development of the eye-antennal disk which gives rise to the adult eye, antenna and head capsule, for transcriptional repression of the Notch receptor ligand Ser and for the self-renewal of cyst stem cells in the testis. In the adult testis, maintains the male identify of adult somatic cyst stem cells. Represses expression and alternative splicing of transformer pre-mRNA, resulting in the production of the male-specific isoform of transcription factor dsx which ensures male-specific transcription of target genes. Plays a role in actin nuclear localization through its involvement in repressing the expression of the kinase Cdi. This maintains the cofilin/actin-depolymerizing factor homolog tsr in its unphosphorylated state which is required for actin nuclear import.

Rabbit

Polyclonal

IgG

Non-conjugated

Protein A or G purified

Recombinant Drosophila melanogaster chinmo protein.

Liquid

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

It differs from different batches. Please contact us to confirm it.

Made-to-order

ELISA, WB

Drosophila melanogaster

Store at -20 °C or -80 °C.

Avoid freeze-thaw cycles.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.